원광대학교 산본병원 원대산본병원블로그

  • 대표전화
대표전화 / 전화예약
031-390-2300
산본치과병원
031-390-2875~6
원광대학교 산본병원

연구성과

특허 출원 및 등록

1. 공개특허 10-2021-0077845, 소변의 알파-씨누클레인 중합체 측정에 의한 파킨슨병 진단 정보의 수집방법 및 그 키트

발표한 학술 논문

2023년
  1. Ho, D.H.; Kim, H.; Nam, D.; Heo, J.; Son, I. Nuclear α-Synuclein-Derived Cytotoxic Effect via Altered Ribosomal RNA Processing in Primary Mouse Embryonic Fibroblasts. Int. J. Mol. Sci. 2023, 24, 2132. https://doi.org/10.3390/ijms24032132
2022년
  1. Ho DH, Nam D, Seo M, Park SW, Seol W, Son I. LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss. Cells. 2022 Mar 2;11(5):861. doi: 10.3390/cells11050861. PMID: 35269482; PMCID: PMC8909553.
2021년
  1. Nam D, Kim A, Han SJ, Lee SI, Park SH, Seol W, Son I, Ho DH. Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson’s disease Animal Cells and Systems, Volume 25, 2021 - Issue 1 Pages 28-36 | Received 14 Oct 2020, Accepted 25 Jan 2021, Published online: 17 Feb 2021
  2. Ho DH, Nam D, Jeong S, Seo MK, Park SW, Seol W, Son I.Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model. Neurobiol Dis. 2021 Mar 26:105349. doi: 10.1016/j.nbd.2021.105349. Online ahead of print. PMID: 33781924
  3. Ho DH, Nam D, Seo MK, Park SW, Seol W, Son I. LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells. Oxid Med Cell Longev. 2021 Jul 8;2021:9969842. doi: 10.1155/2021/9969842. eCollection 2021. PMID: 34306319
  4. Kim H, Sim H, Lee JE, Seo MK, Lim J, Bang Y, Nam D, Lee SY, Chung SK, Choi HJ, Park SW, Son I, Kim J, Seol W. Ciliogenesis is Not Directly Regulated by LRRK2 Kinase Activity in Neurons. Exp Neurobiol. 2021 Jun 30;30(3):232-243. doi: 10.5607/en21003. PMID: 34230223
2020년
  1. Nam D, Lee JY, Lee M, Kim J, Seol W, Son I, Ho DH. Detection and Assessment of α-Synuclein Oligomers in the Urine of Parkinson’s Disease Patients. Journal of Parkinson's Disease, vol. Pre-press, no. Pre-press, pp. 1-11, 2020, Accepted 28 April 2020 | Published: 22 May 2020
  2. Seol W, Kim H, Son I. Urinary Biomarkers for Neurodegenerative Diseases Exp Neurobiol. 2020 Oct 31;29(5):325-333. doi: 10.5607/en20042.